Supplementary material for "Ab initio genotype-phenotype association reveals intrinsic modularity in genetic networks"



This page contains data, softwares and supplementary results for the article "Ab initio genotype-phenotype association reveals intrinsic modularity in genetic networks", published online on 31 January 2006, in Molecular Systems Biology.

Full text is available at http://www.nature.com/msb/journal/v2/n1/full/msb4100047.html

Authors of the paper are Noam Slonim, Olivier Elemento and Saeed Tavazoie. NS and OE have equally contributed to this work.


Data

- Phylogenetic profiles for all 202 bacterial genomes 
- Phenotype profiles ("inf" signifies that it is unknown whether the phenotype is present or absent)
- species ID / species name correspondence table

note: the first line of each phylogenetic_profiles.txt file and of phenotypes_profiles.txt contains the species IDs. Species IDs are not necessarily in the same order in the phylogenetic and phenotype profile files.  The species name associated with each species ID is given in the above correspondance table.


Softwares used in the study

- Iclust (information-based clustering)
- EstI (estimation of mutual information values)


Supplementary results

Motility
- Figure in paper
- All motility clusters
- All Motility GGs

Gram-negative
- Figure in paper
- All Gram-negative clusters
- All Gram-negative GGs

Spore formation
- Figure in paper
- All clusters
- All Spore formation GGs

Oxygen requirement : Aerobic / Facultative / Anaerobic
- Figure in paper
- All aerobic clusters
- All aerobic GGs
- All facultative clusters
- All facultative GGs
- All anaerobic clusters
- All anaerobic GGs

Intracellular pathogenicity
- Figure in paper
- All clusters
- All Intracellular pathogenicity GGs